Our mission is to pioneer new approaches for understanding how trauma affects brainโ€“body systems, and to translate these insights into more effective and accessible interventions. We combine advanced neuroimaging, biobanking, computational modelling, and lived-experience co-design to identify mechanisms of vulnerability and resilience, informing the development of precision therapeutics. Utilizing next-generation technologies, including AI-enabled analysis, data-sharing initiatives, and open science, we aim to transform how trauma-related mental illnesses are understood, diagnosed, and treated.

We develop and evaluate innovative therapeutics, including psychedelic-assisted psychotherapy and precision rehabilitation approaches, in partnership with clinicians, industry, and lived-experience communities. Our research also extends to related and comorbid mental illnesses such as depression, and leverages models of brain injury (e.g., stroke and traumatic brain injury) to investigate how biological trauma contributes to psychopathology and recovery.

Clinical Neuroimaging Biomarkers Lab team photo

Our Scientific and Professional Communities

Organisations and networks we are part of

ACNS ANS BIYOME BPA Bravehearts ISMRM OHBM UQ NIF ACNS ANS BIYOME BPA Bravehearts ISMRM OHBM UQ NIF

Principal Investigator

Lena Oestreich, PhD

Lena Oestreich, PhD

NHMRC Fellow ยท The University of Queensland (UQ)
Group Leader ยท Australian Institute for Bioengineering and Nanotechnology
Senior Lecturer (Assistant Professor) ยท UQ School of Psychology

I am a biological psychologist and computational neuroscientist with a PhD in clinical psychology from the University of New South Wales (UNSW), Sydney. I completed postdoctoral training at the Queensland Brain Institute (QBI) and the UQ Centre for Clinical Research (UQCCR), where I developed expertise in computational psychiatry, clinical neuroimaging, and clinical trial research. My work investigates how trauma alters neural, physiological, and behavioural systems across the lifespan, with the goal of translating these mechanisms into more effective and accessible treatments for trauma-related disorders. I also contribute to psychedelic-assisted therapy studies, leveraging neuroimaging to elucidate mechanisms of action, markers of remission, and potential predictors of long-term therapeutic benefit.

I currently hold a joint appointment as Group Leader at the Australian Institute for Bioengineering and Nanotechnology and the School of Psychology at the University of Queensland, where I lead the Clinical Neuroimaging and Biomarkers Lab. I am committed to open science, equitable participation in research, and advancing interdisciplinary approaches that bridge neuroscience, clinical practice, and technological innovation.

Our Team

A global perspective on neuroscience research

Lab Location (Brisbane)
Photos show team member origins
Lena Oestreich

Lena Oestreich

Principal Investigator

๐Ÿ‡ฉ๐Ÿ‡ช Germany

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Sarah Khalife

Sarah Khalife

PhD Student

๐Ÿ‡ฑ๐Ÿ‡ง Lebanon

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Xuqian Li

Xuqian Li

Postdoc

๐Ÿ‡จ๐Ÿ‡ณ China

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Chrystal Douflias

Chrystal Douflias

PhD Student

๐Ÿ‡ฆ๐Ÿ‡บ Australia

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Hamad Mhanna

Hamad Mhanna

PhD Student

๐Ÿ‡ฏ๐Ÿ‡ด Jordan

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Mamaru Amsalu

Mamaru Amsalu

PhD Student

๐Ÿ‡ช๐Ÿ‡น Ethiopia

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Alice Mok

Alice Mok

PhD Student

๐Ÿ‡ฐ๐Ÿ‡ท South Korea

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AP

Aveechal Prasad

MPhil Student

๐Ÿ‡ฆ๐Ÿ‡บ Australia

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MT

Matthew Thurston

PhD Student

๐Ÿ‡บ๐Ÿ‡ธ United States

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Anthony Paproki

Anthony Paproki

NIF AI and Image Analysis Fellow

๐Ÿ‡ซ๐Ÿ‡ท France

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Arush Honnedevasthana Arun

Arush Arun

NIF Imaging Data Pipelines Fellow

๐Ÿ‡ฎ๐Ÿ‡ณ India

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Ashley York

Ashley York

NIF Ultra-High Field Imaging Fellow

๐Ÿ‡ฆ๐Ÿ‡บ Australia

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Esandi Tennakoon

Esandi Tennakoon

Honours Student

๐Ÿ‡ฑ๐Ÿ‡ฐ Sri Lanka

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AA

Ava Anselme

Honours Student

๐Ÿ‡ฆ๐Ÿ‡บ Australia

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RT

Rain Teo

Honours Student

๐Ÿ‡ธ๐Ÿ‡ฌ Singapore

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Greta Simpson

Greta Simpson

PhD Student

๐Ÿ‡ฎ๐Ÿ‡ช Ireland

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Willow

Willow

Chief Snack Dispenser and Nap Coordinator

๐Ÿ• Australia

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Lab News

Resources

Connect with our work

Funding

Our research is supported by the following organisations.

NHMRC ARC AIBN BBRF Psychology NHMRC ARC AIBN BBRF Psychology